I know here in Asheville anything I could get at a mall store I can find at a locally owned business. Clothes, jewelry, chocolates, books, computers, you name it. I have friends and family that love getting "anything Asheville". Not only can I get something unique to Asheville, my dollars stay in Asheville, I'm helping out a neighbor and I get to meet new people who will remember me when I come back in.
So think local. Support your community and neighbors.